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    Additional Services

NON-INVASIVE PRENATAL TESTING (NIPT)

The Harmony™ prenatal blood test is a new alternative test available for screening chromosomal abnormalities during pregnancy and is available at Grosvenor Medical.

The Harmony™ prenatal blood test uses a small sample of maternal blood to detect DNA within fetal cells (baby cells) circulates in the mother’s blood which are then screened to estimate your risk of common chromosome conditions such as Downs syndrome.

During a pregnancy, cell-free DNA (cfDNA) can be tested to give the most accurate screening approach in estimating the risk of a fetus having a common chromosome condition sometimes called a trisomy. This occurs when there are three copies of a particular chromosome instead of the expected two. The test looks to detect the following trisomies:

Trisomy 21 is the most common trisomy at the time of birth. Also called Down syndrome, it is associated with moderate to severe intellectual disabilities and may also lead to digestive disease, congenital heart defects and other malformations.

Trisomy 18 (Edwards syndrome) and Trisomy 13 (Patau syndrome) are associated with a high rate of miscarriage. These babies are born with severe brain abnormalities and often have congenital heart defects as well as other birth defects. Most affected individuals die before or soon after birth, and very few survive beyond the first year of life.

Sex chromosome conditions. The sex chromosomes (X and Y) determine whether we are male or female. X and Y chromosome conditions occur when there is a missing, extra, or incomplete copy of one of the sex chromosomes. The Harmony with the sex chromosome aneuploidy panel option can assess risk for XXX, XYY, XXYY, XXY (Klinefelter syndrome), and a missing X chromosome in a girl (Turner syndrome).

When should the Harmony™ Prenatal blood test be performed?

The Harmony™ testing can be undertaken any time in pregnancy after 10 weeks gestation.

The test is therefore suitable for any woman who has a viable singleton pregnancy equivalent to a gestation of 10 weeks or more. It is also suitable for the majority of Twin pregnancies.

How will the Harmony™ Prenatal blood test be performed?

The Harmony™ blood test requires a small sample of the mothers blood being taken from a vein in the same way you would when providing a routine sample of blood at your GP practice.

The test is considered non-invasive and carries no risk to the foetal wellbeing unlike invasive testing such as amniocentesis.

You will also be required to receive an ultrasound scan of your baby to con rm the pregnancy is 10 weeks or more gestation, that the fetal heart beat is present, and to confirm a singleton or multiple pregnancy.

Your results will be available within 10 working days of the laboratory receiving your sample.

How accurate is the Harmony Prenatal blood test?

Harmony’s DNA-based technology correctly identifies Down syndrome in more than 99% of cases. By comparison, traditional blood tests can miss as many as 15% of Down syndrome cases in pregnant women.

Harmony is also much less likely than traditional tests to give you a false-positive result, meaning there is much less chance your doctor would recommend follow-up invasive testing, such as amniocentesis.

The Harmony™ test achieves over 99% accuracy and a false-positive rate less than 0.1%.

We regard this latest method of testing as the gold standard in non-invasive prenatal screening.

ADDITIONAL CLINICAL SERVICES

Grosvenor Medical’s team of expert medical practitioners are available to provide additional clinical services that can be closely related to our pregnancy services including the expertise of out Consultant Obstetrician /Gynaecologists and Consultant Urologists. We are able to assist our private patients with the following:

Reproductive Health

Male and Female Infertility Investigations

Recurrent Miscarriage Investigations

Andrology – Sperm Health Assessment

Genetic Testing

Private Sexual Health Screening

Pre & Postnatal Diagnostics

Non-Invasive Prenatal Testing

Cytology / Histopathology

DNA / Paternity Testing

Private Consultations / Second Opinions

Counselling Psychotherapy Consultations